# ChEMBL — AI Connector

ChEMBL publishes 6 MCP tools to Claude. Marketplace availability, tool surface, verification tier, and what Node8 measured against the live endpoint.

Source: https://node8.ai/ai-connectors/healthcare/chembl/

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[AI Connectors](https://node8.ai/ai-connectors/) · [Healthcare & Life Sciences](https://node8.ai/ai-connectors/healthcare/)

# ChEMBL

Bioactivity, targets and mechanism data from the ChEMBL database

Listed in Claude · 6 published tools · Built by Anthropic

[Claude connector docs](https://claude.com/resources/tutorials/using-the-chembl-connector-in-claude) [anthropic.com](https://anthropic.com)

Overview

## What ChEMBL does

ChEMBL is a manually curated database of drug-like compounds with measured activity against biological targets. This Anthropic built connector reaches it without credentials. Compounds can be found by name, ChEMBL identifier or molecular structure; targets by protein, enzyme, receptor or organism; and the quantitative bridge between them, IC50, Ki, EC50 and related measurements, is retrievable for a compound and target pair. Two further calls cover mechanism of action for approved drugs and clinical candidates, and drug search by therapeutic indication. A sixth returns ADMET related molecular properties, with the caveat in its own description that ChEMBL supplies calculated descriptors rather than experimental values.

### Who it is for

Medicinal chemists and pharmacology researchers checking compound activity.

### Tool surface

Six tools with a clear spine: compound\_search and target\_search find entities, get\_bioactivity supplies the quantitative link between them, and get\_mechanism, drug\_search and get\_admet answer narrower questions about approved drugs and drug-likeness.

Availability

## Where ChEMBL is listed

ChEMBL is listed in the Claude connectors directory only. Anthropic has no app under the same domain in the ChatGPT directory; 392 of the 3,150 products here are on both marketplaces, and this is not one of them.

The MCP server behind a Claude connector is usually the same server a ChatGPT app would need, so the absence is a distribution decision rather than a technical one.

Claude listing

## In the Claude connectors directory

ChEMBL publishes 6 tools to Claude. That is a mid-sized surface: 28.1% of the 1,253 Claude-listed connectors expose fewer.

That is exactly the median for Claude-listed connectors under Healthcare & Life Sciences, where 51 publish counts and 6 is the middle of the distribution.

It falls in the 4-6 tools band, which holds 16.2% of the Claude directory.

### Measured against the live endpoint

A direct call to the endpoint returned 6 tools, matching the 6 the listing publishes. Probed 2026-08-07.

#### Tools the server actually returns

-   `compound_search`
-   `get_bioactivity`
-   `target_search`
-   `get_mechanism`
-   `drug_search`
-   `get_admet`

ChEMBL publishes a remote MCP endpoint. Claude connects to it over HTTP; there is nothing to install locally.

Every connector in the Claude directory is remote, all 1,253 of them, so transport is not a differentiator there.

Publisher

Anthropic

Verification

Built by Anthropic (0.7% of the Claude directory)

Filed under

Health & Life Sciences

Endpoint

`https://hcls.mcp.claude.com/chembl/mcp`

Documentation

[Publisher setup docs](https://claude.com/resources/tutorials/using-the-chembl-connector-in-claude)

Published tools

6 · 4-6 tools band

Depth rank in Healthcare & Life Sciences

23 of 51

Snapshot

August 2026

ChEMBL is one of only 9 connectors in the entire Claude directory built by Anthropic itself, 0.7% of the 1,253 listings. Everything else is published by a third party.

In the publisher's words

## How Anthropic describes it

> The ChEMBL Connector gives Claude access to the ChEMBL Database, a manually curated resource of bioactive drug-like compounds with quantitative binding and functional data against biological targets.

Quoted from the connector's own Claude directory listing as captured in August 2026. Node8 did not write it and does not vouch for it.

Same company

## More from Anthropic

### [Anthropic Economic Index](https://node8.ai/ai-connectors/data-analytics/anthropic-economic-index/)

Public data on how Claude usage varies by country and occupation

Claude

### [bioRxiv](https://node8.ai/ai-connectors/healthcare/biorxiv/)

Preprint search across bioRxiv and medRxiv

Claude

### [Clinical Trials](https://node8.ai/ai-connectors/healthcare/clinical-trials/)

Search ClinicalTrials.gov by condition, sponsor, investigator or eligibility

Claude

### [CMS Coverage](https://node8.ai/ai-connectors/healthcare/cms-coverage/)

Medicare Part B coverage determinations from the CMS database

Claude

Nearby

## Other Healthcare & Life Sciences connectors

### [CMS Coverage](https://node8.ai/ai-connectors/healthcare/cms-coverage/)

Medicare Part B coverage determinations from the CMS database

Claude

### [Benchling](https://node8.ai/ai-connectors/healthcare/benchling/)

Benchling research data through its own scientific AI chat

Claude

### [bioRxiv](https://node8.ai/ai-connectors/healthcare/biorxiv/)

Preprint search across bioRxiv and medRxiv

Claude

### [Clinical Trials](https://node8.ai/ai-connectors/healthcare/clinical-trials/)

Search ClinicalTrials.gov by condition, sponsor, investigator or eligibility

Claude

### [Convoke](https://node8.ai/ai-connectors/healthcare/convoke/)

Biopharma development programmes and their upcoming catalysts

Claude

### [ICD-10 Codes](https://node8.ai/ai-connectors/healthcare/icd-10-codes/)

ICD-10-CM and ICD-10-PCS lookup, search and validation

Claude

[All 101 Healthcare & Life Sciences connectors](https://node8.ai/ai-connectors/healthcare/)

This is an independent catalogue entry compiled by Node8 from ChEMBL's public marketplace listing as it stood in August 2026. Listing facts come from the marketplaces; the comparisons against the rest of the directory and any live-endpoint measurements are Node8's. Node8 is not affiliated with Anthropic, and inclusion here is not an endorsement.

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