Who it is for
Biologists, bioinformaticians, and computational researchers who would rather state an analysis than assemble the tooling for it.
Run bioinformatics tools and pipelines described in plain language
Overview
smarts.bio connects a bioinformatics platform to ChatGPT so analyses can be described in words instead of scripted. Sequence work covers BLAST searches, GC content, open reading frames, and domain detection across DNA, RNA, and protein.
Beyond single searches, the app aligns reads from whole exome and RNA sequencing, calls and annotates variants, and runs quality control and other pipelines with several stages. Files can be uploaded into a workspace and the results opened in interactive viewers, with FASTA, BAM, VCF, PDB, and CSV among the supported formats. Gene, literature, and patent searches sit alongside the analysis tools.
Use requires a connected smarts.bio account. Jobs that take a long time continue in the background, and files remain in the account's own workspace.
Biologists, bioinformaticians, and computational researchers who would rather state an analysis than assemble the tooling for it.
It runs actual pipelines on uploaded data rather than explaining how the analysis would be done.
Availability
smarts.bio: AI for biology is listed in the ChatGPT apps directory only. smarts.bio has no connector under the same domain in the Claude directory; 392 of the 3,150 products here are on both marketplaces, and this is not one of them.
ChatGPT apps are built on MCP, and the same server can back a Claude connector, so the absence is a distribution decision rather than a technical one.
ChatGPT listing
Same company
Run bioinformatics tools and pipelines described in plain language
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This is an independent catalogue entry compiled by Node8 from smarts.bio: AI for biology's public marketplace listing as it stood in August 2026. Listing facts come from the marketplaces; the comparisons against the rest of the directory and any live-endpoint measurements are Node8's. Node8 is not affiliated with smarts.bio, and inclusion here is not an endorsement.
Node8 builds MCP servers end to end: deciding which tools are worth exposing, the authentication and permission model, the review submissions, and the onboarding that gets them used. One server serves ChatGPT, Claude, and Microsoft Copilot.