Who it is for
Computational chemists and structural biologists running prediction jobs.
AI Connectors · Healthcare & Life Sciences
Boltz API
Structure prediction, library screening and binder design from chat
Overview
What Boltz API does
Boltz publishes models for biomolecular structure prediction, and this is the official server for its hosted API. The described workflows are structure and binding interaction prediction, screening small molecule or protein libraries against a target, and de novo design of small molecules and protein binders. Each workflow estimates its cost before running, which matters because compute for this work is metered rather than trivial, and finished results download into the workspace as structured files rather than being summarised in a reply. Ten tools are declared. An API key is required and the endpoint refuses anonymous listing requests.
Tool surface
Ten tools cover job submission, cost estimation and result retrieval according to the listing, but a 401 blocks enumeration, so that division is the publisher's account of it.
Availability
Where Boltz API is listed
Boltz API is listed in the Claude connectors directory only. Boltz has no app under the same domain in the ChatGPT directory; 392 of the 3,150 products here are on both marketplaces, and this is not one of them.
The MCP server behind a Claude connector is usually the same server a ChatGPT app would need, so the absence is a distribution decision rather than a technical one.
Claude listing
In the Claude connectors directory
Boltz API publishes 10 tools to Claude. That is a mid-sized surface: 45% of the 1,253 Claude-listed connectors expose fewer.
The median Claude-listed connector filed under Healthcare & Life Sciences publishes 6, so this one runs 4 tools above its bucket's median and ranks 10th of 51 by tool count.
It falls in the 7-10 tools band, which holds 14.6% of the Claude directory.
Boltz API publishes a remote MCP endpoint. Claude connects to it over HTTP; there is nothing to install locally.
Every connector in the Claude directory is remote, all 1,253 of them, so transport is not a differentiator there.
- Publisher
- Boltz
- Verification
- Verified partner (37.8% of the Claude directory)
- Filed under
- Health & Life Sciences
- Endpoint
-
https://mcp.boltz.bio/mcp - Documentation
- Publisher setup docs
- Published tools
- 10 · 7-10 tools band
- Depth rank in Healthcare & Life Sciences
- 10 of 51
- Snapshot
- August 2026
Boltz API carries partner verification in the Claude directory, which 474 of 1,253 listings do (37.8%). That is a review step past self-publishing, not an Anthropic-built server.
In the publisher's words
How Boltz describes it
The official Model Context Protocol (MCP) server for the Boltz API. Predict molecular structures and binding interactions, screen small-molecule and protein libraries against a target, and design small molecules and protein binders — all from chat. Each workflow estimates cost before running, then downloads structured results to your workspace when the job completes.
Quoted from the connector's own Claude directory listing as captured in August 2026. Node8 did not write it and does not vouch for it.
Same company
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Boltz
Structure prediction, molecular screening and binder design
ChatGPT
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This is an independent catalogue entry compiled by Node8 from Boltz API's public marketplace listing as it stood in August 2026. Listing facts come from the marketplaces; the comparisons against the rest of the directory and any live-endpoint measurements are Node8's. Node8 is not affiliated with Boltz, and inclusion here is not an endorsement.
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