Who it is for
Computational chemists and structural biologists running prediction, screening, or design work.
AI Connectors · Education & Research
Boltz
Structure prediction, molecular screening and binder design
Overview
What Boltz does
Boltz brings biomolecular modeling into a conversational workflow, driven from Codex. It predicts structure and binding for complexes involving proteins, RNA, DNA, and small molecule ligands.
Beyond prediction, it ranks libraries of small molecules or proteins against a chosen target, which covers screening work. It also generates new candidates: small molecules, peptides, antibodies, nanobodies, and custom protein binders, each returned with a structure and confidence metrics.
The listing exposes separate skills for structure and binding, screening, design, small molecule ADME, status checks, and command line setup. Example requests name specific targets, among them an EGFR mutant against a known inhibitor and nanobodies aimed at a SARS-CoV-2 epitope.
What stands out
Prediction, library ranking, and new molecule design sit behind one connector, with confidence metrics on the output.
Availability
Where Boltz is listed
Boltz is listed in the ChatGPT apps directory only. Boltz has no connector under the same domain in the Claude directory; 392 of the 3,150 products here are on both marketplaces, and this is not one of them.
ChatGPT apps are built on MCP, and the same server can back a Claude connector, so the absence is a distribution decision rather than a technical one.
ChatGPT listing
In the ChatGPT apps directory
- Developer
- Boltz
- Filed under
- Education & Research
- Listed since
- June 2026
- Authentication
- Authenticates when installed
- Website
- boltz.bio
- Policies published
- Privacy policy · Terms of service
- Official listing
- Open in ChatGPT
- Snapshot
- August 2026
Named skills
Boltz declares 8 named skills, which puts it in the 6.7% of ChatGPT-listed apps that do.
- boltz-check-status
- boltz-cli-setup
- boltz-protein-design
- boltz-protein-screen
- boltz-small-molecule-adme
- boltz-small-molecule-design
- boltz-small-molecule-screen
- boltz-structure-and-binding
Example prompts from the listing
- Predict EGFR L858R binding to osimertinib
- Design nanobodies for a SARS-CoV-2 RBD epitope
- Design selective JAK2 binders from Enamine REAL
Same company
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This is an independent catalogue entry compiled by Node8 from Boltz's public marketplace listing as it stood in August 2026. Listing facts come from the marketplaces; the comparisons against the rest of the directory and any live-endpoint measurements are Node8's. Node8 is not affiliated with Boltz, and inclusion here is not an endorsement.
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