Who it is for
Translational genomics researchers sizing cohorts and validating targets.
AI Connectors · Healthcare & Life Sciences
Helix GenoSphere
Aggregate carrier counts across 500,000 exome sequenced participants
Overview
What Helix GenoSphere does
Helix GenoSphere links exome sequencing for a large research cohort to longitudinal electronic health record data. The connector queries it at the aggregate level only: gene-level carrier counts, pathogenic variant counts, membership of curated gene panels, and patient counts for any concept drawn from standardised medical vocabularies covering conditions, drugs and laboratory results. Every response is aggregated and statistically de-identified, with small groups suppressed so participants cannot be re-identified. No SQL is involved and nothing writes back. Five tools are declared. The listing carries the partner tier and links to documentation.
Tool surface
The probe was stopped by a bot filter at the CDN, returning 403 without the MCP server ever answering, so the five tools remain a published figure.
Availability
Where Helix GenoSphere is listed
Helix GenoSphere is listed in the Claude connectors directory only. Helix has no app under the same domain in the ChatGPT directory; 392 of the 3,150 products here are on both marketplaces, and this is not one of them.
The MCP server behind a Claude connector is usually the same server a ChatGPT app would need, so the absence is a distribution decision rather than a technical one.
Claude listing
In the Claude connectors directory
Helix GenoSphere publishes 5 tools to Claude, a deliberately narrow surface; only 22.3% of the 1,253 Claude-listed connectors expose fewer.
The median Claude-listed connector filed under Healthcare & Life Sciences publishes 6, so this one sits one tool below its bucket's median, 30th of 51.
It falls in the 4-6 tools band, which holds 16.2% of the Claude directory.
Helix GenoSphere publishes a remote MCP endpoint. Claude connects to it over HTTP; there is nothing to install locally.
Every connector in the Claude directory is remote, all 1,253 of them, so transport is not a differentiator there.
- Publisher
- Helix
- Verification
- Verified partner (37.8% of the Claude directory)
- Filed under
- Health & Life Sciences
- Endpoint
-
https://mcp.hrn-production.helix.com/mcp - Documentation
- Publisher setup docs
- Published tools
- 5 · 4-6 tools band
- Depth rank in Healthcare & Life Sciences
- 30 of 51
- Snapshot
- August 2026
Helix GenoSphere carries partner verification in the Claude directory, which 474 of 1,253 listings do (37.8%). That is a review step past self-publishing, not an Anthropic-built server.
In the publisher's words
How Helix describes it
Bring Helix GenoSphere™ — a growing research clinico-genomic dataset of more than 500,000 exome-sequenced participants with linked longitudinal EHR data — directly into Claude. Query gene-level carrier counts and pathogenic variants, determine target genes on curated panels, search standardized medical vocabularies (conditions, drugs, labs), and obtain privacy-protected patient counts for any concept. All responses are aggregated and statistically de-identified, with small groups suppressed to protect participant privacy. A read-only window into population-scale genomics, no SQL required.
Quoted from the connector's own Claude directory listing as captured in August 2026. Node8 did not write it and does not vouch for it.
Nearby
Other Healthcare & Life Sciences connectors
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KORE
Query a lab's extracted instrument and protocol metadata
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Synthesize Bio
Generate simulated human gene expression data from a prompt
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Turquoise
Benchmark negotiated healthcare rates across payers and providers
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Pearl Pet Care
Pet health answers checked by licensed veterinarians
ChatGPT
This is an independent catalogue entry compiled by Node8 from Helix GenoSphere's public marketplace listing as it stood in August 2026. Listing facts come from the marketplaces; the comparisons against the rest of the directory and any live-endpoint measurements are Node8's. Node8 is not affiliated with Helix, and inclusion here is not an endorsement.
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