Who it is for
Structural biologists and biochemists who search the PDB by description rather than accession code.
AI Connectors · Education & Research
Natural language search across Protein Data Bank structures
Overview
Protplex puts a natural language layer over the Protein Data Bank. Instead of matching on identifiers or exact field values, it works from condensed profiles of each entry describing structure, function and biochemistry.
The searchable dimensions listed are function, structure, chemistry, source organism, assembly, bound ligands and experimental context, across a collection the record puts at more than 240,000 structures. A single query can therefore combine constraints that would otherwise mean several separate searches, as in the record's own example of archaeal enzymes carrying a particular cofactor.
The record describes search and retrieval, with no mention of structure prediction, alignment or visualisation.
Structural biologists and biochemists who search the PDB by description rather than accession code.
Distilled profiles let one query mix organism, ligand and experimental context together.
Availability
Protplex is listed in the ChatGPT apps directory only. Straintest has no connector under the same domain in the Claude directory; 392 of the 3,150 products here are on both marketplaces, and this is not one of them.
ChatGPT apps are built on MCP, and the same server can back a Claude connector, so the absence is a distribution decision rather than a technical one.
ChatGPT listing
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This is an independent catalogue entry compiled by Node8 from Protplex's public marketplace listing as it stood in August 2026. Listing facts come from the marketplaces; the comparisons against the rest of the directory and any live-endpoint measurements are Node8's. Node8 is not affiliated with Straintest, and inclusion here is not an endorsement.
Node8 builds MCP servers end to end: deciding which tools are worth exposing, the authentication and permission model, the review submissions, and the onboarding that gets them used. One server serves ChatGPT, Claude, and Microsoft Copilot.